Imperial College London, Exhibition Road, SW7 2AZ
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ASCENT™ 3D Printed Unicondylar Knee with Cementless durable fixation
As the only knee implant to combine a 3D printed articulating surface with biomimetic fixation, ASCENT’s cementless unicondylar knee arthroplasty (UKA) creates the conditions for optimized implant fixation and a durable bone foundation.
We are the only company to take full advantage of 3D printing with our unitary manufacturing process, forming the articulating surface and bone fixing structures in one process. This achieves optimal bone ingrowth, stronger fixation, increased stability and a simplified supply chain.
ASCENT™ uses our patented biomimetic & surface printing platform technologies, built on 10 years of peer-reviewed 3D printing development.
ASCENT™ utilises OSSTEC's proprietary 3D printing technology, uniquely 3D printing the articulating surface and biomimetic fixation to reduce failures.
Cementless UKA achieves better fixation with fewer radiolucencies than cemented implants. 1
Streamlined workflow with the CLARITY™ instrumentation offers efficient surgery with minimized learning curve for new surgeons.
Unitary 3D printing offers a simplified, cost saving supply chain and eliminates the risk of delamination of fixation coatings seen in other devices. 2
ASCENT utilises OSSTEC's proprietary 3D printing technology, uniquely 3D printing the articulating surface and biomimetic fixation to reduce failures.
Cementless UKA achieves better fixation with fewer radiolucencies than cemented implants. 1
Streamlined workflow with the CLARITY instrumentation offers efficient surgery with minimized learning curve for new surgeons.
Unitary 3D printing offers a simplified, cost saving supply chain and eliminates the risk of delamination of fixation coatings seen in other devices. 2
Designed to grow UKA usage
Innovative technology, built with surgeons, for efficient surgery
Optimized fixation
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Press-fit 3D printed fixation surface with HA on both femur & tibia
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Built on 3D printing research spanning 30+ papers at Imperial
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Optimized osseointegration from cell scale to human scale
Easy adoption
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Tested in 20 cadaver labs with US & European surgeons
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Short learning curve and familiar technique compatible with robotic systems
Trusted materials
CoCr Articulating surface
Vitamin-E polyethylene
Titanium tibial component
Built for outpatient surgery
Capture market growth in outpatient surgery & the ASC
Streamlined costs
Reduce consumable costs & tray sterilization
Operating efficiency
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2 tray system & streamlined surgery improves operating room efficiency
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Eliminate cement to cement to save time & cost
Market shows 25% growth
in hospital outpatients & ASC knee patients
Designed to grow UKA usage
Innovative technology, built with surgeons, for efficient surgery
Optimized fixation
-
Press-fit 3D printed fixation surface with HA on both femur & tibia
-
Built on 3D printing research spanning 30+ papers at Imperial
-
Optimised osseointegration from cell scale to human scale
Easy adoption
-
Tested in 20 cadaver labs with US & European surgeons
-
Short learning curve and familiar technique compatible with robotic systems
Trusted materials
-
CoCr Articulating surface
-
Vitamin-E polyethylene
-
Titanium tibial component
Built for outpatient surgery
Capture market growth in outpatient surgery & the ASC
Streamlined costs
Reduce consumable costs & tray sterilisation
Operating efficiency
2 tray system & streamlined surgery improves operating room efficiency.
Eliminate cement to cement to save time & cost
Market shows 25% growth
in hospital outpatients & ASC knee patients
Economic benefits
Lower operating room consumable expenditure
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UKA Is more cost effective than TKA. 16
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Save 10 minutes per surgery, averaging $750 saving per surgery. 12-15
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Cementless knee arthroplasty is more cost effective than cemented. 17
10 minutes saved per surgery
Reduce implant unit costs and eliminate cement costs
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All metal components are 3D printed to reduce number of manufacture processes and simplify supply chain.
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Fully cementless procedures require no cement consumable costs, saving $500 per surgery. 11
$500 saving cement costs
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OSSTEC’s cementless UKA has clear health economic benefits
Compared to cemented UKA:
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Risk of revision due to pain is 40% less likely than for cemented UKA at 10 years. 6
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Registry data shows risk of revision due to aseptic loosening in cementless UKA is 50% of that for cemented UKA at 10 years. 6
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Cementless UKA enables easier revision to primary TKA.
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No risk of incorrectly cementing the joint.
Faster recovery
Compared to TKA:
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30-day readmission rates for UKA are half of those for TKA. 18
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Shorter hospital stay, more natural gait and more likely to return to sports following UKA compared to TKA. 19-21
More satisfied patients
Clinical benefits
UKA has clinical benefits for patients compared to TKA.
Improved patient-reported outcomes and patient satisfaction compared to Total Knee Replacement (TKA).
Reduced mortality, length of stay, complications and readmission rates compared to TKA. 4
Up to 50% of patients only have osteoarthritis disease in one compartment and would be suitable for a UKA, rather than a TKA. 5
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Cementless UKA has better 10-yr implant survival compared to cemented UKA. 6
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Revision due to aseptic loosening is 50% less for cementless UKA than cemented UKA. 6
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Removal of the cementation phase optimizes surgical worktlow, minimising operating time.
OSSTEC Contour
3D printed articulating surface is smoother than cast components, improves fixation and eliminates delamination risk
OSSTEC Adapt
Minimized COGS & Supply chain. Reduces implant unit costs and improves supply chain robustness
CLARITY™ instrumentation
Innovative 3D Printing to reduce failures and supply chain complexity. Developed over 10 years at Imperial College London across 33 published studies.
OSSTEC unify & HA
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Bone gripping fixation surface
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Maximizes initial fixation and bone adhesion
References
1. Liddle AD et al., Bone Joint J, 2013 | 2. OSSTEC 2023. Preliminary Clinical Literature Search Report. OS-000589-DD | 3. Liddle AD et al., Bone Joint J, 2015 | 4. Liddle AD et al., The Lancet, 2014 | 5. Stoddart JC et al., Osteoarthritis Cartilage, 2021 | 6. Mohammad HR et al., Acta Orthopaedica, 2020 | 7. Ghouse S et al., Appl Mater Today, 2019 | 8. Reznikov N et al., Biomaterials, 2019 | 9. Munford MJ et al., Bone Joint Res, 2022 | 10. Bhalekar RM et al., Bone Joint J, 2021 | 11. Lawrie CM et al., Bone Joint J, 2019 | 12. Pandit H et al., J Bone Joint Surg Am, 2013 | 13. Stempin R et al., Open Orthop J, 2017 | 14. Akan B et al., Adv Orthop, 2013 | 15. Ting NT et al., J Arthroplasty, 2012 | 16. Burn E et al., BMJ Open, 2018 | 17. Asokan A et al., Bone Jt Open, 2021 | 18. Drager J et al., J Arthroplasty, 2016 | 19. Walton NP et al., J Knee Surg, 2006 | 20. Lombardi AV Jr et al., Clin Orthop Relat Res, 2009 | 21. Jones GG et al., Bone Joint J, 2016 | 22. Campi S et al., Knee Surg Sports Traumatol Arthrosc, 2017 | 23. Scopus | 24. Australian National Joint Registry, 2024 | 25. QS world university rankings 2024 and 2025
Technology Benefits
Innovative 3D Printing to reduce failures and supply chain complexity. Developed over 10 years at Imperial College London across 33 published studies.
Unitary 3D manufacture
Minimized COGS & supply chain. Reduces implant unit costs and improves supply chain robustness.
